EFFECT OF BODY FAT PERCENTAGE AND BODY MASS INDEX ON ORTHODONTIC TOOTH MOVEMENT

Not yet recruiting

Conditions: TO ASSESS ORTHODONTIC TOOTH MOVEMENT IN PATIENTS IN WHOM UPPER 1ST PREMOLARS ARE EXTRACTED

Registration Number: CTRI/2021/04/033170

Lead Sponsor: SRI HASANAMBA DENTAL COLLEGE AND HOSPITAL

Brief Summary: Orthodontic tooth movement is defined as â€œtheresult of a biologic response to interference in the physiologic equilibrium ofthe dentofacial complex by an externally applied force.â€ Numerous factors, suchas age, drug consumption, diet, several systemic conditions and other intrinsicgenetic factors are considered to influence the rate of orthodontic toothmovement. Continuous efforts are beingmade to find out the factors influencing orthodontic tooth movement. Body MassIndex (BMI) is one of the factors which is thought to influence orthodontictooth movement. Many studies have been conducted to correlate Body Mass Index(BMI) with orthodontic tooth movement, but the results were either inconclusiveor debatable. This was mainly due to the inappropriate methodologiesapplied in these studies.Another possible reason could be that; inmost of these studies, the Body Mass Index (BMI) was used as a reference todifferentiate normal and obese individuals. Although the Body Mass Index (BMI,kg/m2) is widely used as a proxy measure of adiposity, it is ameasure of excess weight relative to height, rather than excess body fat. Valuesof body weight adjusted to height in square mm is BMI i.e. (BMI; in kg/m2).BMI values in excess of 25 and 30 are considered to indicate overweight andobesity respectively. A BMI value of 18.5 to 24.9 is considered to be normal.The main assumption of BMI guidelines is that body mass divided by height in m2,is closely associated with body fatness. However, some individuals who areoverweight may not be overfat (e.g., bodybuilders). Others have BMIâ€™s withinthe normal range but may have a high percentage of their body weight as fat.Hence the drawbacks of thesestudies were that they only considered BMI as a measure of adiposity todifferentiate between obese and normal individuals and did not consider BodyFat percentage (BF%) levels of the studied individuals.Increase inBody Fat percentage (BF%) levels has been correlated with the increase in serumleptin levels.Studies also have found that the leptin which isavailable in saliva controls bone metabolism which in turn has an inverseeffect on the orthodontic tooth movement.Hence the Body Fatpercentage (BF%) levels could indirectly play a vital role in the orthodontictooth movement. So far in the scientific literature, no studies have beenreported evaluating the relationship of Body Fat percentage (BF%) on orthodontic toothmovement. Hence with the above background, this study is designed to assess therelationship between BMI, Body Fat percentage (BF%) levels and orthodontictooth movement.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

1.Subjects who are willing to participate in the study.
2.Subjects who will undergo fixed orthodontic treatment with Pre-adjusted Edgewise Appliance (PEA) with 0.022Êºslot MBT prescription.
3.Subjects in the age range of 15-35 years.
4.Normal weight subjects with BMI (18.5Kg/m2 or more and less than 25Kg/m2) and overweight or obese subjects with BMI (25Kg/m2 or more).
5.Subjects with normal Body Fat percentageâ€™s (BF%) 10 to < than 20% for males and 20 to < than 30% for females and high to very high Body Fat percentageâ€™s (BF%) 20% or more for males and 30% or more for females.
6.Subjects who will be entering the retraction stage after completion of the leveling and alignment (Ist phase).
7.Subjects in whom maxillary 1st premolar extraction will be indicated and who will have at least 5mm of space for en masse retraction of maxillary anteriors.

Exclusion Criteria

1.Previous history of orthodontic treatment.
2.Presence of any syndromes or systemic diseases.
3.Presence of any signs and symptoms of periodontal disease.
4.Long term use of phenytoin sodium, cyclosporin, anti-inflammatory drugs, steroids and calcium channel blockers.
5.Poor oral hygiene for more than 2 visits.
6.Smoking and other habits such as chewing pan.
7.Pregnant and lactating women.
8.Subjects who are on statins or lipid lowering agents.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
EFFECT OF HIGH OR LOW BODY FAT PERCENTAGE AND BODY MASS INDEX ON ORTHODONTIC TOOTH MOVEMENT	THREE MONTHS FROM THE START OF EN MASSE RETRACTION OF MAXILLARY ANTERIOR TEETH

Secondary Outcome Measures

Name	Time	Method
TO COMPARE THE EFFECT OF BODY FAT PERCENTAGE ON ORTHODONTIC TOOTH MOVEMENT AND BODY MASS INDEX ON ORTHODONTIC TOOTH MOVEMENT	THREE MONTHS FROM THE START OF EN MASSE RETRACTION OF MAXILLARY ANTERIOR TEETH

Trial Locations

Locations (1): SRI HASANAMBA DENTAL COLLEGE AND HOSPITAL, HASSAN
🇮🇳
Hassan, KARNATAKA, India
SRI HASANAMBA DENTAL COLLEGE AND HOSPITAL, HASSAN
🇮🇳Hassan, KARNATAKA, India
DR REJI ABRAHAM
Principal investigator
9947357788
rejiabm@gmail.com