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Clinical Trials/NCT05966987
NCT05966987
Enrolling By Invitation
Phase 1

Assessment of Different Orthodontic Tooth Movements Assisted With Low-level Laser Therapy vs. Injectable Plasma-rich Fibrin: A Comparative Clinical Investigation

Al-Azhar University1 site in 1 country82 target enrollmentAugust 2023

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Injectable Plasma-rich Fibrin Versus Low-Level Laser Therapy on Othodontic Movement
Sponsor
Al-Azhar University
Enrollment
82
Locations
1
Primary Endpoint
assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy on the accelration rate of different orthodontic tooth movements by millimeter
Status
Enrolling By Invitation
Last Updated
2 years ago

Overview

Brief Summary

The present prospective clinical study will be undertaken for assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy onthe rate of different orthodontic tooth movements,

Detailed Description

The present prospective clinical study will be undertaken for assessment of the effect of application of Inject able plasma-rich fibrin versus Low-Level Laser Therapy on the rate of different orthodontic tooth movements, namely: canine retraction, mandibular incisors leveling and alignment, maxillary molar distalization and maxillary incisor intrusion.

Registry
clinicaltrials.gov
Start Date
August 2023
End Date
September 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

farouk ahmed hussein

Principal Investigator

Al-Azhar University

Eligibility Criteria

Inclusion Criteria

  • A- leveling and alignment Eligibility criteria
  • Complete permanent dentition (third molars not included).
  • Moderate mandibular anterior crowding (with Little's irregularity index score greater than 4 mm) who required nonextraction approach in the mandibular arch.
  • No tooth size, shape or root abnormalities visible on patient's radiographic records.
  • No spaces in the mandibular arch.
  • No blocked out tooth that did not allow for placement of the bracket at the initial bonding appointment.
  • No required management with interproximal stripping, intermaxillary elastics, open NiTi springs, and removable or extra-oral devices. Maxillary molar distalization Inclusion criteria:
  • Age ranges from 14 to 17 years.
  • Bilateral Class II molar relationship.
  • Skeletal Class I or mild Class II relationship.

Exclusion Criteria

  • Exclusion criteria:
  • Patients who required surgery to correct skeletal discrepancies.
  • Patients with congenital dentoskeletal disorders.
  • Missed or mutilated teeth in maxillary arch.
  • Patients with poor oral hygiene and/or periodontally compromised patients Severe dental crowding that necessitates an extraction approach
  • Abnormal anteroposterior and vertical relationships;
  • Patients with cleft lip and palate, anomalies, and syndromes;
  • Previous orthodontic
  • Regular medications intake that could interfere with otm. -

Outcomes

Primary Outcomes

assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy on the accelration rate of different orthodontic tooth movements by millimeter

Time Frame: 6 months

Study Sites (1)

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