EEG controlled triage in the ambulance for acute ischemic stroke

Recruiting

Conditions: cerebral infarction
Stroke
10007963

Registration Number: NL-OMON52630

Lead Sponsor: Academisch Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 729

Inclusion Criteria

- Suspected acute ischemic stroke (or known acute ischemic with a large vessel
occlusion of the anterior circulation, for phase 3);
- Onset of symptoms or, if onset not witnessed, last seen well <24 hours ago
(for phase 3 and 4);
- Age of 18 years or older;
- Written informed consent by patient or legal representative (deferred for
phase 3 and 4).

Exclusion Criteria

Injury or active infection of electrode cap placement area.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary end point of the study is the area under the ROC curve of the<br /><br>theta/alpha ratio for diagnosis of LVO-a, based on dry electrode EEG performed<br /><br>by paramedics in the ambulance in suspected AIS patients. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Sensitivity, specificity, PPV and NPV of the theta/alpha ratio, and test<br /><br>characteristics of other existing EEG data based algorithms for LVO-a detection<br /><br>(e.g. Weighted Phase Lag Index, delta/alpha ratio);<br /><br>- Logistical and technical feasibility of paramedics performing dry electrode<br /><br>cap EEG in the ambulance in suspected AIS patients;<br /><br>- Developing one or more novel EEG data based algorithms with an optimal<br /><br>diagnostic accuracy for LVO-a detection in suspected AIS patients with ambulant<br /><br>dry electrode cap EEG.</p><br>