A randomized controlled clinical trial to study the effect of Rasnadyo Guggulu in the management of ardhavabhedaka with special reference to simple migraine.

Ayurveda has given prime importance to Shira where the Prana i.e. life

exists. Acharya Charaka considered Shira as the supreme important and major

part of the body which is known as Uttamang. Ardhavabhedaka is a Shiroroga which is mentioned in multiple

literature of Ayurveda.

Usually there is radiating and throbbing  pain in  head in Ardhavabhedaka.

It is sadhya  type of Shiroroga . Ardha means half side of the head and Bhedaka means perforating type of

pain it is the disease having symptoms of Uttamanga ardhabhaga sambhedana toda, bhrama Rasnadyo Guggulu  is the drug which is  Shiroroghar.   Therefore, it can be used to treat Ardhavabhedaka. It contains rasna, guggulu, devdaru, guduchi, suntha, eranda.

Individually have various guna like vataghna, pittaghna, kaphaghna, shulaghana, tridoshaghna which when taken together will definitely found to be beneficial in treating ardhavabhedaka, so rasnadyo guggulu can be used as best alternative to caffeine ergotamine tablets.

Inclusion criteria a)Patients having Lakshanas of Ardhavabhedaka or simple migraine.

b)Patients between age group of 18-60 years.

c)Patients will be included irrespective of sex, religion and caste.

B]Exclusive criteria:

a) Patients with complicated migraine, hemiplegic migraine.

b) Patients age below 18 years and above 60 years.

c)Patients having a history of head trauma and other types of headaches.

d) Patients having any inflammatory diseases in nose ,PNS ,eyes and ears.

e) Patients suffering from other diseases like HIV,DM,HTN, pregnant

women .

Patient will be selected from signs and symptoms mentioned in classical texts and are selected irrespective of sex, socioeconomic status and community, written consent from patient will be taken to prior to study. Computerised generated sampling technique will be used. Total 70 number of patients will be selected and divided into two groups, named as Group A (trial group) and Group B (control group). Rasnadyo guggulu Group A (trial group) with dose 300 mg equivalent to dose 1 mg caffeine and 100 mg ergotamine tablet Group B (Control group) once a day will be given to patients. Both drugs will be administered in tablet form for 15 days. Observations will be done on day 0 day, 5th day, 10th day and 15th day and follow up on 31st day. Result of study will be drawn on the basis of criteria of assesment and statistical analysis. Discussion will be done on the basis of observations and result obtained during the treatment. Summary will be drawn and whole thesis work will be summarized. Conclusion will be drawn strictly on basis of statistical analysis and will be unbiased