Evaluation of the effect of budesonide nebulizer in patients with exacerbated COPD
Phase 2
Recruiting
- Conditions
- Chronic obstructive pulmonary disease.Chronic obstructive pulmonary disease with (acute) exacerbation
- Registration Number
- IRCT20180523039800N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients with exacerbated COPD following respiratory infection
15-70 years old
Disease severity of moderate to severe based on GOLD scoring
Exclusion Criteria
Exacerbated COPD with a cause other than respiratory infection
History of asthma, allergic rhinitis or atopy
History of systemic corticosteroids more than 1500 micrograms/ day over the past month
Patients with decreased consciousness
Known psychological disorder and inability to cooperate in the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Variation in peak expiratory flow rate. Timepoint: 30 and 60 minutes, and 3, 6, 12, and 24 hours later. Method of measurement: Peak flow meter device.
- Secondary Outcome Measures
Name Time Method Variation in FEV1 percentage. Timepoint: 30 and 60 minutes and 3, 6, 12 and 24 hours later. Method of measurement: Spirometry.