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Efficacy of cryobiopsy for peripheral pulmonary lesions

Phase 3
Recruiting
Conditions
Peripheral pulmonary lesion
Registration Number
JPRN-UMIN000049329
Lead Sponsor
ational Cancer Center Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
660
Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients who have a past history of any local treatment (e.g., surgery, radiation therapy) for bronchial or pulmonary lesions ipsilateral to the target lesion. 2) Patients who have poorly controlled comorbidities (i.e., severe bronchial asthma, active pulmonary infection, low pulmonary function presenting with chronic respiratory failure, unstable angina, post-acute myocardial infarction, heart failure, and severe bleeding tendency). 3) Patients who have psychosis, psychiatric symptoms, or dementia that interfere with daily life. 4) Patients who take anticoagulant and/or antiplatelet medications and cannot discontinue them for the procedure. However, as for antiplatelet agents, only acetylsalicylic acid may be continued. 5) Other patients who are judged by the attending physician to be inappropriate as the subjects.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Diagnostic yield by histology
Secondary Outcome Measures
NameTimeMethod
1) Sensitivity, specificity, and accuracy as to malignancy diagnosis 2) Diagnostic yield by specimen type 3) Cumulative diagnostic yield by number of tissue specimens 4) Incidence of (serious) adverse events 5) Procedure time 6) Success rate of genetic testing 7) Patient reported outcomes
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