Identifying Biomarkers for Endothelial Dysfunction in Women With Preeclampsia
- Conditions
- Endothelial Function (FMD)PreeclampsiaRetinal Vessels
- Registration Number
- NCT07084727
- Lead Sponsor
- University Hospital, Antwerp
- Brief Summary
Every pregnancy has a major impact on a woman's heart and blood vessels due to changes required by the body to maintain proper blood flow between mother and foetus. When the placenta does not work properly, preeclampsia can occur. An important first symptom is high blood pressure. Women who have experienced preeclampsia are at higher risk of developing blood pressure and heart problems later on. Therefore, it is very important to detect changes in the blood vessel system so that they can be treated promptly and correctly. We aim to do this by using a new, non-invasive eye test that examines the blood vessels of the retina.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 60
- at least 18 years old
- willing to undergo vascular assessments
- informed consent signed
- Unwilling to provide informed consent
- Open-angle glaucoma
- Epilepsia
- (gestational) Diabetes
- Multiple pregnancies
- Fetal malformations
- Hypercholesterolemia
- Kidney disease
- Auto-immune disorders
- Connective tissue diseases
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Retinal biomarkers Baseline Early (retinal) biomarkers for cardiovascular risk in patients with preeclampsia, assessed by DVA.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Antwerp University Hospital
🇧🇪Edegem, Antwerp, Belgium
Antwerp University Hospital🇧🇪Edegem, Antwerp, BelgiumStudies cardiologieContact+32 3 821 40 74studies.cardiologie@uza.be