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Comparison of Tab.Labetalol and Tab.Nifedipine for Management of Postpartum Hypertension

Phase 3
Conditions
Postnatal Hypertension
Interventions
Registration Number
NCT02426177
Lead Sponsor
Dow University of Health Sciences
Brief Summary

To compare effectiveness of oral labetalol and oral nifedipine for management of postpartum hypertension.

Detailed Description

A comparison of oral labetalol and oral nifedipine for management of postpartum hypertension. Which drug is more effective in lowering blood pressures in patient with postpartum hypertension.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
98
Inclusion Criteria
  • all women with postpartum hypertension as a continuation of pregnancy induced hypertension,eclampsia, pre-eclampsia or new onset de-novo postpartum hypertension,of any parity.
  • age group between 18-48.
  • after informed consent.
Exclusion Criteria
  • all women with chronic hypertension, uncontrolled and un treated medical disorders will be excluded.
  • conditions in which drugs labetalol and nifedipine is contraindicated.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
group ALabetaloltab.labetalol is given to the patient with postpartum hypertension in dose of 100 mg 6 hourly increased to maximum 600 mg in 24 hours
group BNifedipinetab.nifedipine is given to the patient with postpartum hypertension in the dose of 10 mg twice a day to maximum dose of 60 mg per 24 hours
Primary Outcome Measures
NameTimeMethod
Blood Pressure less than 140/90 mm of hg24 hours

less than 140/90 mm of hg

Secondary Outcome Measures
NameTimeMethod
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