Comparison of Oral Labetalol and Oral Nifedipine for Postpartum Hypertension Management
试验速览
- 阶段
- 3 期
- 入组人数
- 98
- 主要终点
- Blood Pressure less than 140/90 mm of hg
研究概览
简要总结
To compare effectiveness of oral labetalol and oral nifedipine for management of postpartum hypertension.
详细描述
A comparison of oral labetalol and oral nifedipine for management of postpartum hypertension. Which drug is more effective in lowering blood pressures in patient with postpartum hypertension.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 48 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •all women with postpartum hypertension as a continuation of pregnancy induced hypertension,eclampsia, pre-eclampsia or new onset de-novo postpartum hypertension,of any parity.
- •age group between 18-
- •after informed consent.
排除标准
- •all women with chronic hypertension, uncontrolled and un treated medical disorders will be excluded.
- •conditions in which drugs labetalol and nifedipine is contraindicated.
研究组 & 干预措施
group A
tab.labetalol is given to the patient with postpartum hypertension in dose of 100 mg 6 hourly increased to maximum 600 mg in 24 hours
干预措施: Labetalol (Drug)
group B
tab.nifedipine is given to the patient with postpartum hypertension in the dose of 10 mg twice a day to maximum dose of 60 mg per 24 hours
干预措施: Nifedipine (Drug)
结局指标
主要结局
Blood Pressure less than 140/90 mm of hg
时间窗: 24 hours
less than 140/90 mm of hg
次要结局
未报告次要终点
研究者
fariha javed
resident
Dow University of Health Sciences