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临床试验/NCT07157228
NCT07157228尚未招募不适用

Clinical Characteristics, Etiologies, and Outcomes of Patients With Haematochezia at Al-Rajhi University Hospital.

Assiut University0 个研究点目标入组 70 人开始时间: 2025年10月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
70
主要终点
To identify the incidance of haematochezia in patients presented to Al-Rajhi University Hospital.

研究概览

简要总结

Haematochezia is the passage of bright red or maroon blood or blood clots from the rectum, usually originates from a source in lower parts of the gastrointestinal (GI) tract

  • In addition, haematochezia can be seen in patients with brisk upper gastrointestinal bleeding (UGIB). The underlying etiology can vary from life threatening variceal bleeding to clinically insignificant haemorrhoidal bleeding . The most common etiology is diverticular bleeding, which accounts for 20% to 55% of cases, followed by intestinal ischemia, inflammatory bowel diseases, anorectal disorders, and neoplasia, which each accounting for around 10% of cases
  • LGIB can be mild and intermittent or moderate or severe . Patients with mild bleeding can be electively evaluated as outpatients. While, those with severe bleeding should be hospitalized for management Acute or severe LGIB has an incidence of 20-30 cases/100,000 person years and accounts for 20% of GI bleeds (7-8). The overall mortality rate of LGIB is 2-4% .

Clinical data available at the time of initial patient evaluation can be used to identify patients at high risk for severe bleeding and other adverse outcomes. Several scoring systems have been developed to assess risk in acute LGIB .

To the best of our knowledge, no Egyptian study has addressed the outcome of patients with haematochezia presented at the endoscopy units or has evaluated the clinical utility of risk scores in assessment of patients admitted to hospitals with acute haematochezia. Therefore, we need to study the short-term outcomes of patients with haematochezia (and their predictors) after being managed.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients >18 years old presenting at the GIT Endoscopy Unit withfresh bleeding per rectum or admitted at Tropical Medicine & Gastroenterology Department, Al-Rajhi University Hospital in a period of one year.

排除标准

  • Patients younger than 18 years old.
  • Patients with isolated melena without haematochezia.
  • Patients who refuse colonoscopy
  • Patients who refuse to participate in the study.

结局指标

主要结局

To identify the incidance of haematochezia in patients presented to Al-Rajhi University Hospital.

时间窗: baseline

To identify the incidance of haematochezia in patients presented to Al-Rajhi University Hospital.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Reham Rashad Mohamed Mahmoud

residant doctor

Assiut University

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