Effect of Eccentric Strengthening Exercise in Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- Not Applicable
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- pain intensity, pressure pain threshold, strength, range of motion, and functional disability and depression severity of knee osteoarthritis patients.
研究概览
简要总结
We plan to carry out a five weeks randomized controlled trial. We will compare the effectiveness between eccentric strengthening exercise along with conventional care and conventional care only for patient with knee osteoarthritis. This study aims to determine the knee osteoarthritis-related sociodemographic characteristics, baseline comparison at pretest and determine the effectiveness of eccentric strengthening exercise on pain, pressure pain threshold, strength, range of motion, functional disability, six minutes walk test and depression severity of knee osteoarthritis patients during posttest and follow-up also. We expect better treatment outcome after 15 sessions of intervention for knee osteoarthritis patients who receive eccentric strengthening exercise along with conventional care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Presence of Unilateral/Bilateral Knee osteoarthritis for at least six months, according to American College of Rheumatology criteria.
- •Tibiofemoral osteoarthritis-related knee pain and discomfort.
- •Capable of walking without the use of gait aids, and able to flex the knee beyond 90 degrees.
- •Anterior posterior bilateral standing radiograph presenting Kellgren and Lawrence Grade II/III Knee osteoarthritis.
- •Providing consent of completion five week intervention and capable to carry with upon it.
- •Without suffering any unusual cardiac response during the six minute walk test.
排除标准
- •Any knee surgery performed in the previous twelve months.
- •Lumbar radiculopathy, vascular claudication, severe anterior knee pain resulting from isolated patella femoral syndrome or chondromalacia in the knee, as well as further neurological, muscular, or joint conditions that could impair the function of the lower limbs.
- •Visible malformation of the knee, either varus or valgus.
- •Received hyaluronic acid or corticosteroid injections within three months of study enrollment; within two months, added new OTC or prescription painkillers.
- •Mental or language obstacles limiting protocol implementation.
- •BMI over 30.
结局指标
主要结局
pain intensity, pressure pain threshold, strength, range of motion, and functional disability and depression severity of knee osteoarthritis patients.
时间窗: 6 months
次要结局
- Range of motion, and six-minutes walk test and depression severity(6 months)
研究者
Kazi Md Azman Hossain
Jashore University of Science and Technology (JUST)