JPRN-UMIN000035865已完成未知
Optimal regimens of glucocorticoids tapering for remission induction therapy in patients with severe systemic lupus erythematosus : multi-center randomized open label trial - Optimal regimens of glucocorticoids tapering in patients with systemic lupus erythematosus
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 44
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable(—)
- 性别
- All
入选标准
- 未提供
排除标准
- •1) Persons who did not obtain consent 2) Patients with poorly controlled complications 3) Pregnant or lactating women 4) Male and female with pregnancy plan within 52 weeks
研究者
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To study the effects of 2 standard treatment-timing strategies for glucocorticoïd dosage on androgen concentration in CAH childreCongenital adrenal hyperplasia (AGS)NL-OMON25245Radboudumc, Department of pediatric endocrinology50
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Avoiding over and undertreatment by optimizing of the timing ofglucocorticoïd treatment in children with cnogenital adrenal hyperplasiaCongenital adrenal hyperplasia (CAH) is a disorder of adrenal steroidsynthesis leading to cortisol deficiency and an increase in androgenproduction.Treatment in children consists of hydrocortisone substitutionthereby also restoring the negative feedback on the pituitary gland andconsequently normalize androgen production. There is still no evidenceabout the best timing of hydrocortisone use: The highest dosage ofhydrocortisone in the morning or the highest dosage at nightEUCTR2018-004802-24-NLRadboud University Nijmegen Medical Centre50
招募中
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BLISS-POSTSystemic Lupus ErythematosusJPRN-jRCTs071190045Tanaka Yoshiya100
