Mother to Child Transmission of Antibody to Covid-19 The TRAB CoV-19 Study.
- Conditions
- AntibodyCordMaternalVaccine
- Registration Number
- NCT05305261
- Lead Sponsor
- National University of Malaysia
- Brief Summary
This is a prospective clinical study aiming to investigate on the transplacental antibody transmission post Covid-19 infection during pregnancy.
- Detailed Description
Covid -19 infection has been a significant public health burden as it shifted the paradigm of infectious diseases aiming to control the spread and enhance public immune protection. The introduction of Covid -19 vaccination in December 2020 aimed to combat the infection, thus tremendously helping to flatten the disease worldwide. Channeling the vaccine for the obstetrics field is one of the hallmark strategies to reduce maternal morbidity and mortality. The efficacy of vaccination for the pregnant lady has been established. However, fetus protection via transmission of the antibody during pregnancy is still uncertain. Therefore, this study aims to consolidate further evidence of transplacental antibody post-maternal vaccination aiming for fetal protection following delivery.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 197
- term pregnancies at 37 weeks or more
- vaccinated 2 doses
- in labour
- unvaccinated
- preterm labour less than 37 weeks
- multiple pregnancies
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Maternal to Neonatal Transmission Antibody Covid-19 Study - The TRAB CoV-19 30 minutes after delivery Quantification of Covid-19 antibody levels in maternal and cord blood samples
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UKM Medical Center
🇲🇾Kuala Lumpur, W.Persekutuan, Malaysia