COMPARATIVE STUDY OF CLINICAL OUTCOMES AFTER DAY 3 CLEAVAGE STAGE AND DAY 5 BLASTOCYST STAGE EMBRYO TRANSFER IN IN-VITRO FERTILIZATION AT THE FERTILITY UNIT OF FEDERAL MEDICAL CENTRE, ABUJA.

Not Applicable

Recruiting

• Conditions: Fertility-female

• Registration Number: PACTR202206898636627
• Lead Sponsor: DR. MICHAEL JOHN OFEM

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-10
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 104

Inclusion Criteria

1. Age must be between 18-39 years.
2. Normal baseline hormonal profile (FSH, LH, E2, Prolactin, and AMH).
3. Normal uterine cavity confirmed by hysterosalpingogram or hysteroscopy.

Exclusion Criteria

1.Maternal age above 39years
2.Women who did not fulfill inclusion criteria.
3. Women who had endocrine or metabolic disorder.
4. Women who had a history of chemotherapy or Radiotherapy
5.Women with uterine anomalies, or focal endometrial lesions (fibroid, polyp, adhesion, endometritis etc).
6.Patients with more than 3 unsuccessful IVF attempts
7.Patients with any contraindication for pregnancy
8.Refusal or inability to comply with the requirements of the study protocol for any reason, including scheduled clinic visits and laboratory tests

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Positive pregnancy test conducted two weeks after embryo transfer<br>2.Pregnancy confirmation via ultrasound revealing intrauterine gestation at 2 weeks after positive pregnancy test (4 weeks following embryo transfer)<br>3.Ongoing pregnancy by 20 weeks gestation.<br>SECONDARY OUTCOMES1.Fertilization rates<br>2.Cleavage rates <br>3.Blastulation rates<br>4.Multiple pregnancy rates<br>5.Early pregnancy losses including: ectopic pregnancy and miscarriages occurring before 20 weeks<br>

Secondary Outcome Measures

Name	Time	Method
2 SECONDARY OUTCOMES<br>1.Fertilization rates<br>2.Cleavage rates <br>3.Blastulation rates<br>4.Multiple pregnancy rates<br>5.Early pregnancy losses including: ectopic pregnancy and miscarriages occurring before 20 weeks<br>