Relationship Between Postoperative Delirium and Heart Function in Valvular Surgery

• Conditions: Valvular Surgery
• Interventions: Other: No intervention

• Registration Number: NCT05211934
• Lead Sponsor: Beijing Anzhen Hospital

Brief Summary

Delirium is an acute brain lesion characterized by abnormalities of consciousness, attention, cognition and sensation. Many brain diseases such as stroke, traumatic brain injury and intracranial hypertension can lead to cardiac insufficiency, arrhythmia and heart failure. The incidence of postoperative delirium in patients undergoing cardiac surgery is high. Postoperative delirium is a manifestation of brain function injury. The effect of postoperative delirium on postoperative cardiac function in patients undergoing cardiac surgery is worthy of further discussion.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-01
• Study Start: 2022-01-01
• Study First Submitted: 2022-01-14
• Study First Submitted QC: 2022-01-14
• Last Update Submitted: 2022-01-14
• Study First Posted: 2022-01-27
• Last Update Posted: 2022-01-27
• Primary Completion: 2024-07-01
• Study Completion: 2024-07-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Patients undergoing valvular surgery
• Age between 60 to 75

Exclusion Criteria

• Have a history of cerebral infarction before operation
• Cardiac function was seriously impaired before surgery
• Neuropsychiatric disorders were present before surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
The group without delirium	No intervention	-
The group with delirium	No intervention	-

Primary Outcome Measures

Name	Time	Method
heart function	up to 60 days	Doses of norepinephrine, epinephrine, dopamine, dobutamine and vasopressin

Trial Locations

Locations (1)

Anzhen hospital, Beijing; 🇨🇳 Beijing, Beijing, China