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The pathophysiology of post-surgery delirium in elderly people

Not Applicable
Recruiting
Conditions
post&#45
surgical delirium
delirium&#44
inflammation&#44
elderly
Registration Number
TCTR20190102001
Lead Sponsor
Ratchadapisek Sompot Fund, Faculty of Medicine, Chulalongkorn University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

-patients age 55 or above who admit into the hip fracture pathway and have a hip fracture operation then transfer into the surgical ICU, understand Thai language, APACHEII>8.

Exclusion Criteria

current delirium, severe dementia, or active major psychiatric illness.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
changes in blood gas and electrolytes in the patients at risk to develop delirium 1-4 days venous blood gas, electrolyte panel,changes in blood gas and electrolytes in the patients at risk to develop delirium 1-4 days venous blood gas, electrolyte panel,changes in blood gas and electrolytes in the patients at risk to develop delirium 1-4 days venous blood gas, electrolyte panel
Secondary Outcome Measures
NameTimeMethod
To examine changes in levels of cytokines, and IgA/IgM responses in the patietns at risk 1-4 days Eotaxin, MIP-1, sIL-RA, TRYCATs IgM/IgA
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