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临床试验/NCT00108784
NCT00108784已完成不适用

The Effect of Decreases in Energy Density on Weight Loss and Weight Maintenance

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2003年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
100
试验地点
1
主要终点
Weight loss

研究概览

简要总结

This study will test the hypothesis that reducing the energy density of the diet by incorporating more water-rich foods will result in: 1) greater weight loss and weight maintenance; 2) greater diet satisfaction and satiety; and 3) more healthful dietary patterns than reducing dietary fat alone.

详细描述

Energy density refers to the amount of calories (energy) in a given weight of food. For the same amount of energy, a larger volume (weight) of food can be consumed if the food or diet is low in energy density than if the food or diet is high in energy density. The two nutrients that have the largest impact on energy density are fat and water. Foods high in fat and low in water content are typically high in energy density, whereas foods low in fat and high in water content, such as fruits and vegetables, are low in energy density. This study will examine whether there are increased benefits for weight loss and weight maintenance when the ad libitum consumption of water-rich foods is added to a reduced-fat diet, thus making it even lower in energy density.

Comparisons: Reduced-energy-dense diet and Reduced-fat diet

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
Female
接受健康志愿者
是

入选标准

  • •Healthy women
  • •BMI (body mass index) 30 through 40 kg/m2
  • •Normal blood pressure
  • •LDL (low density lipoprotein)-cholesterol < 90th percentile recommendations
  • •Triglycerides, fasting blood glucose, and all other blood values within normal ranges
  • •Able to participate in low to moderate physical activity.

排除标准

  • •Heart disease
  • •Diabetes - type I or II
  • •High blood pressure
  • •Renal or kidney disease
  • •Gastrointestinal disease
  • •Blood clotting disorder
  • •Liver disease or cirrhosis
  • •Any oral steroids
  • •Gout (requiring treatment)
  • •Lung disease
  • •Cancer within the last 5 years
  • •Thyroid disease

结局指标

主要结局

Weight loss

Weight maintenance

次要结局

  • Changes in diet: quality and patterns, energy density, and fat content
  • Changes in lipids
  • Satisfaction with the two different dietary methods for weight loss

研究者

研究点 (1)

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