Effect of glucose lowering drugs on some blood parameters in diabetic patients with and without retinal problems.
Phase 4
- Conditions
- Health Condition 1: null- Type 2 diabetes with and without retinopathy
- Registration Number
- CTRI/2018/05/013601
- Lead Sponsor
- ady Hardinge Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Type 2 diabetic patients with and without retinopathy taking treatment for atleast one year coming to Medicine and Ophthalmology Department.
Exclusion Criteria
1. Patients with uncontrolled hypertension
or recent acute cardiovascular event .
2. Pregnancy.
3. Unconscious patients/moribund patients.
4. Patients in whom fundus examination is not possible due to cataract or opacification of media.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the correlation of tight glycaemic control by antidiabetic medications with serum levels of MCP-1 and cathepsin-D in type 2 diabetes with and without retinopathy. <br/ ><br> <br/ ><br>Timepoint: 2 months
- Secondary Outcome Measures
Name Time Method 1. To correlate levels of serum MCP 1 and cathepsin D with diabetic retinopathy . <br/ ><br> <br/ ><br>2. To assess the quality of life in diabetic patients with and without retinopathy by using questionnaire (WHOQOL-BREF). <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: 2 months