A Nutrition-Based Approach to Reduce Heart Disease Risk Among Overweight African Americans: Use of Soul Food Plant-Based or Omnivorous Diets to Address Cardiovascular Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiovascular Disease Risk Factors
- Sponsor
- University of South Carolina
- Enrollment
- 159
- Locations
- 1
- Primary Endpoint
- Cardiovascular Disease Prevention based on dietary approach.
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This study addresses two challenges seen among African American (AA) participants during previous weight loss and dietary interventions aimed at reducing cardiovascular disease (CVD) risk: poor weight loss results and high attrition rates. Investigators will target both of these challenges by using a randomized design to compare a plant-based dietary intervention (vegan diet) vs. an omnivorous (omni) diet and by focusing on culturally-tailored food choices for AA adults living in the South. Therefore, the objective of the study is to conduct a culturally-tailored, randomized trial examining how a vegan diet affects CVD risk factors and weight as compared with an omni diet. The study will randomize overweight AA adults (n=130) to follow one of two different diets (vegan or omni) for 24 months. Investigators will accomplish objectives and test hypotheses by following two specific primary aims:
Primary Aims: Using a randomized design, determine the impact at 12 months of two different, culturally tailored diets (n=65 omni and n=65 vegan) on changes in:
-
Risk factors for CVD, including LDL cholesterol and blood pressure; and
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Body weight.
Secondary Aim
-
Examine long-term changes in CVD risk factors and body weight at 24 months.
Investigators
Brie Turner-McGrievy
Associate Professor
University of South Carolina
Eligibility Criteria
Inclusion Criteria
- •Self-identify as African American
- •Be between the ages of 18-65 years
- •Body Mass Index between 25- 49.9 kg/m2
- •Live in the Columbia, SC/Midlands area
- •Be able to attend all monitoring and weekly class visits
- •Be willing to be randomized to either diet
Exclusion Criteria
- •Currently following a vegan diet
- •Diagnosed with diabetes that is controlled by medication
- •Currently pregnant or breastfeeding (or plan to become pregnant in the next 24 months)
- •Under the age of 18 years old
- •Over the age of 65 years old
- •Currently participating in a weight loss program
- •Has lost more than 10 pounds in the past 6 months
- •Diagnosed with stroke or heart attack
Outcomes
Primary Outcomes
Cardiovascular Disease Prevention based on dietary approach.
Time Frame: Two years
Which dietary approach (vegan or omni) best targets both cardiovascular disease prevention and weight loss among overweight African Americans.