Inhibitory sensory-motor links in the human brai
Recruiting
- Conditions
- Geen aandoening maar onderzoek richt zich op inhibitiemechanismen bij gezonde deelnemersbut rather focuses on a fundamental question regarding mechanisms of inhibition.The aim of the current research does not pertain to a specific pathology
- Registration Number
- NL-OMON47324
- Lead Sponsor
- niversiteit Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
between 18-45 years old.
Exclusion Criteria
(History of) epilepsy
psychopathology
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The following electrophysiological correlates of inhibition are of interest:<br /><br><br /><br>Stop N1: This is the modulation of the N1 (electrophysiological negative peak)<br /><br>by stopping success. Or more specifically, the degree to which the N1 is larger<br /><br>for successful as opposed to failed stops. This modulation is interpreted as<br /><br>characterizing the potentiated inhibitory link between sensory (auditory or<br /><br>visual cortex, depending on the specific SST variant) and motor cortex (under<br /><br>control of a tonically active right frontal cortex).<br /><br><br /><br>Stop N2: This is the modulation of the N2 by stopping success. More<br /><br>specifically, the degree to which the N2 is larger for successful as opposed to<br /><br>failed stops. This modulation is interpreted as characterizing inhibition<br /><br>related activity within the right frontal cortex.</p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>