The effect of cardiovascular response to sedation with dexmedetomidine, midazolam and atomidite in cataract surgery

Phase 3

Recruiting

Conditions: Cataract surgery.
Unspecified disorder of vitreous body
H43.9

Registration Number: IRCT20180416039326N20

Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 90

Inclusion Criteria

Patients aged 35 to 85 years
Patients who are candidates for phycoemolysis cataract surgery
Patients undergoing local anesthesia and sedation in this surgery have Class 1 and 2 of the American Anesthesia Association
Patients with controlled blood pressure

Exclusion Criteria

History of any allergy to the drug used in the design
History of drug addiction, alcohol, benzodiazepine
Pregnancy
Congestive heart failure
History of head trauma
Glaucoma
Hypotension
Evidence of increased intracranial pressure
Psychosis
Schizophrenia
Active upper respiratory tract infection
Asthma
Chronic respiratory disease

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sedation level based on ramsay score. Timepoint: Every 5 minutes during surgery. Method of measurement: Ramsay score.

Secondary Outcome Measures

Name	Time	Method
Arterial pressure. Timepoint: Before intervention, every 5 minutes after the intervention and every 10 minutes after the end of the intervention for 30 minutes. Method of measurement: Pressure gauge.;Oxygen saturation. Timepoint: Before intervention, every 5 minutes after the intervention and every 10 minutes after the end of the intervention for 30 minutes. Method of measurement: Pulse oximeter.;Heart rate. Timepoint: Before intervention, every 5 minutes after the intervention and every 10 minutes after the end of the intervention for 30 minutes. Method of measurement: Pulse oximeter.;Intensity of pain. Timepoint: Before intervention, every 5 minutes after the intervention and every 10 minutes after the end of the intervention for 30 minutes. Method of measurement: Universal Pain assessment tool.;Recovery time. Timepoint: After completing the intervention until the withdrawal from the recovery. Method of measurement: Minute Numbers.