Comparition the impact of Steroid and intraarticular ozon on improving the symptoms of osteoarthritis of knee
- Conditions
- ????? ?????? ???? ????.Osteoarthritis of knee
- Registration Number
- IRCT20100827004641N18
- Lead Sponsor
- Physical Medicibe and Rehabilitaion Research Center of Tabriz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Moderate Knee Osteoarthritis (grade two or three based Radiographic classification (Kellegren and Lawrence)
Existence of symptoms in favor of Knee Osteoarthritis for at least 3 months
Minimum score of 3 in the criterion (VAS)
Absence of Inflammatory Rheumatic diseases
45 years old and older
Satisfaction of patients participating in the study
Failure to respond to Conservative drug treatments and physiotherapy lasted for 6 months
Severe Osteoarthritis (grade 4 candidates for joint replacement surgery)
Rheumatic disease Clearly
Visible deformity of the knee Ankylosis
Contraindications to Ozone include: Hyperthyroidism , Thrombocytopenia ,Pregnancy , Recent heart attack history ,G6PD Deficiency
Definitive and partial Contraindications to Steroid injection include: Bacteremia, Sepsis, Intra articular or pre uricular infection, History of post injection Allergy, Intra articular or Osteochondral fracture at the injection site, Severe Joint destruction in Injection site , Artificial joint , Uncontrolled Coagulation disorders Specific skin lesion at the injection site
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount af Reduce in pain after injection. Timepoint: Immediately before injection and 1 month after injection and 6 months after injection. Method of measurement: Western Ontario and McMaster Universities Arthritis Index (WOMAC)questionare.
- Secondary Outcome Measures
Name Time Method Improvement of function of Knee. Timepoint: Immediately before injection and one and six months after injection. Method of measurement: Western Ontario and McMaster Universities Arthritis Index (WOMAC)questionare.