Role of certain blood tests(serum TWEAK and hematologic markers) in predicting the severity of acute pancreatitis
Not Applicable
- Conditions
- Health Condition 1: K85- Acute pancreatitis
- Registration Number
- CTRI/2020/01/022591
- Lead Sponsor
- JIPMER intrumural fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients over the age of 18 with acute pancreatitis
presenting within 72 hours of onset of symptoms, admitted to the surgery
emergency will be included in the study.
Exclusion Criteria
patients on antiplatelet therapy, autoimmune diseases,
hematologic diseases, HIV positive and patients on immunosuppression
will be excluded from the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method THE PRIMARY OUTCOME VARIABLES ARE values of serum TWEAK, Immature granulocyte <br/ ><br>percentage, Neutrophil to lymphocyte ratio and mean platelet volume.Timepoint: the time points include blood investigations at admission and 24 hours after admission
- Secondary Outcome Measures
Name Time Method THE SECONDARY OUTCOME VARIABLE IS THE VALUES OF SERUM PROALCITONINTimepoint: NO APPLICABLE
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways does serum TWEAK activate in acute pancreatitis severity progression?
How do hematologic markers like NLR compare to Ranson score in predicting acute pancreatitis severity?
Which specific hematologic markers (e.g., platelet count, lymphocyte percentage) correlate with acute pancreatitis severity in CTRI/2020/01/022591?
Do elevated serum TWEAK levels correlate with increased risk of organ failure in acute pancreatitis patients?
What role do other TNF superfamily members (e.g., TNF-α, TRAIL) play in acute pancreatitis prognosis compared to TWEAK?