Muscle-Atrophy, Physical Performance, and RelatedAlterations in Metabolic Milieu, Inflammaging andBiological Age in ISS Crew Members - MuscleHealth

Institut für Luft- und Raumfahrtmedizin0 个研究点目标入组 16 人开始时间: 2021年6月8日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Astronaut group:
•- Astronauts with a planned mission with a minimum of 5 months and a maximum of one year.
•Master Athlete group:
•- Regular training (>4 hrs per week) and participation in master athletics events.
•- Age (+/- 2 years) and sex matched to one participant of the astronauts
•- Body mass index = 28 kg/m²
•Non-physically active group:
•- Physical activity limited to 20 kilocalories per kg/Bodyweight per week
•- Age (+/- 2 years) and sex matched to one participant of the astronauts
•- Body mass index =28 kg/m²
•All groups:
•- Ability to perform VO2max testing, as defined by local med-ops
•- Ability to consent
•- Agreement and signed informed consent before the study

•Severe injuries or abnormalities of the lower extremity that interfere with muscle strength testing or vertical jump testing
•Any debilitating disease, such as cancer or severe auto-immune diseases (use of anti-inflammatory drugs, statins therapy) that are likely to affect the inflammatory / anti-inflammatory balance
•Any chronic infectious disease (hepatitis, HIV) that is likely to affect the inflammatory / anti-inflammatory balance

发起方

Institut für Luft- und Raumfahrtmedizin