Effect of three different amounts of glucose during operation in small childre
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Neonates undergoing major abdominal and thoracic surgeries
- Registration Number
- CTRI/2015/01/005360
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 45
Inclusion Criteria
1.Full term neonates
2.Emergency and elective surgery
3.Haemodynamically stable prior to surgery
4.Blood glucose and electrolyte concentration within normal range.
Exclusion Criteria
1.Preterm
2.Infants of diabetic mothers
3.Inadequate optimisation (hydration, haemodynamics, blood glucose & electrolytes) in pre-operative period
4.Neonates with anticipated gross haemodynamic instability.
5.Neonates in whom arterial arterial cannulation is contraindicated or fails.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Arterial Blood Glucose comparisonTimepoint: Pre-operative and at the end of surgery
- Secondary Outcome Measures
Name Time Method Acid-base parameters (pH, Base deficit, bicarbonate, lactate)Timepoint: Pre-operative and at the end of surgery;Biochemical parameters (free fatty acid, plasma ketone bodies)Timepoint: Pre-operative and at the end of surgery;Elctrolytes (sodium, potassium, chloride, bicarbonate, anion gap)Timepoint: Pre-operative and at the end of surgery;Endocrine stress markers (Glucagon, Insulin, Cortisol)Timepoint: Pre-operative and at the end of surgery