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临床试验/NCT00700609
NCT00700609终止2 期

Family-Based Treatment of Depressed Adolescents: An Empirical Study With Norwegian Adolescents in Specialty Mental Health Care

Helse Stavanger HF2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2008年6月最近更新:
适应症

试验速览

阶段
2 期
状态
终止
入组人数
20
试验地点
2
主要终点
Hamilton Depression Rating scale (HAM-D, 17 items)

研究概览

简要总结

The purpose of this project is to assess the effectiveness of a family-based therapy (Attachment based family therapy-ABFT) for Norwegian adolescents (13-17 years) referred to specialist mental heath clinics.

详细描述

Depression is a major public health concern among adolescents. Research suggests that it not only is prevalent among adolescents (as many as 20% of adolescents have a depressive episode by the age of 18), but its effects last well into adulthood. Although available studies of psychosocial and pharmacological interventions show promise, there are concerns regarding their effectiveness and possible side effects like increase in suicidal ideation. Family conflict is not only an effect of depression, but also a risk factor for depression. High conflict and dysfunction, have consistently been shown to increase risk for depression. As such, family treatments that target risk and protective factors (e.g., quality of parent-child interaction, parental monitoring) for depression seem promising to reduce depression. The current study is a randomized clinical trail aimed at assessing the effectiveness of a 12-week family based intervention for depressed adolescents (Attachment based family therapy- ABFT). Adolescents referred to specialist mental health hospital in south-west Norway (Stavanger University Hospital) will be randomized to either ABFT or treatment as usual (TAU). Therapists administering both the experimental and control group intervention are regular staff clinicians. Outcome assessments would be carried out at baseline, 6, 12 and 26 weeks by raters blind to the condition of the treatment.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
13 Years 至 17 Years(Child)
性别
All
接受健康志愿者

入选标准

  • 13-17 years
  • Referred to specialist mental health hospital
  • HAM-D score of >14
  • Meets diagnostic criteria for major depressive disorder or depression NOS
  • Have a parent or guardian willing to participate

排除标准

  • Suicidal and require in-patient care
  • Low intellectual abilities
  • Current psychosis
  • primary caregiver unwilling to participate

结局指标

主要结局

Hamilton Depression Rating scale (HAM-D, 17 items)

时间窗: Baseline, 6, 12 and 26 weeks

次要结局

  • Beck depression Inventory (BDI-II)(Bi-weekly for 12 weeks)
  • Kiddie- SADS (diagnostic interview)(Baseline and 26 weeks)

研究者

申办方类型
Other Gov
责任方
Sponsor

研究点 (2)

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