Intravenous Lidocaine Reduces Remifentanil and Propofol Requirements Without Altering the Electrical Stapedial Reflex Threshold in Pediatric Cochlear Implants
Overview
- Phase
- Phase 4
- Intervention
- Na CL 0.9%
- Conditions
- Anesthesia
- Sponsor
- Wahba bakhet
- Enrollment
- 70
- Primary Endpoint
- Remifentanil consumption
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The stapedius reflex protects the ear from the loud noise. The measurement of the intraoperative electrically evoked stapedial reflex threshold (ESRT) during pediatric cochlear implants (CIs) is used to confirm that the implant is functioning correctly and determine the maximum comfortable level . Total intravenous anesthesia (TIVA) with propofol and remifentanil is frequently used for pediatric CIs as it does not suppress the ESRT. However, high doses of remifentanil exacerbates postoperative pain and increased opioid consumption.
Detailed Description
Total intravenous anesthesia (TIVA) with propofol and remifentanil is frequently used for pediatric CIs as it does not suppress the ESRT. However, high doses of remifentanil exacerbates postoperative pain and increased opioid consumption.
Investigators
Wahba bakhet
Lectrure of anesthesia
Ain Shams University
Eligibility Criteria
Inclusion Criteria
- •ASA I and II children
Exclusion Criteria
- •uncontrolled hypertension, diabetes mellitus, liver disease, kidney disease, heart disease, allergy to lidocaine
Arms & Interventions
Na CL 0.9%
group C
Intervention: Na CL 0.9%
Liocaine
Group Lid
Intervention: Lidocaine
Outcomes
Primary Outcomes
Remifentanil consumption
Time Frame: at the end of the surgey
microgram per kilogram
Secondary Outcomes
- ESRT responses(After insertion of the electrode and after reversal of any residual muscle relaxant (TOF response > 0.9),)