Lidocaine Reduces Muscle Tremor Caused by Electric Energy Devices, Which is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring During Endoscopic Thyroid Lateral Neck Dissection
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- dose of lidocaine
研究概览
简要总结
In recent years, the application of intraoperative recurrent laryngeal nerve monitoring in thyroid surgery has greatly reduced the complications of recurrent laryngeal nerve injury. The use of intraoperative neurological monitoring requires the reduction of the dose of neuromuscular blockade, which often leads to muscle tremors during the application of electrical energy, which affects the fine separation around the muscles. This study explored the effect of local application of lidocaine on reducing muscle tremor during surgery and its optimal dose.
详细描述
According to the random number method, eligible patients were randomly divided into 2 groups. Group A was the conventional surgery group, and Group B was the lidocaine group. The operative time for the separation of the sternocleidomastoid muscle from the two groups of patients was analyzed, as well as the length of time for the search for the accessory nerve and the effect of intraoperative nerve monitoring on the EMG signal.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Thyroid papillary carcinoma
- •Lateral cervical lymph node metastasis
- •The diameter of the metastatic lymph nodes is less than 3cm
- •Without internal jugular vein invasion
排除标准
- •Lidocaine allergy sufferers
研究组 & 干预措施
Lidocaine group
Anesthesia induction was performed according to conventional nerve monitoring neuromuscular blockade doses and lateral neck dissection was performed. When local muscle tremors occur, lidocaine is injected locally to eliminate muscle tremors.
干预措施: Lidocaine (Drug)
结局指标
主要结局
dose of lidocaine
时间窗: At the end of surgery
dose of lidocaine
Anatomical time of accessory nerve
时间窗: At the end of surgery
Anatomical time of accessory nerve
Number of nerve signal loss cases
时间窗: At the end of surgery
Number of nerve signal loss cases
dose of muscle relaxant drugs
时间窗: At the end of surgery
dose of muscle relaxant drugs
The satisfaction of sternocleidomastoid muscle separation
时间窗: At the end of surgery
The visual score was 5 points for the most satisfaction and 0 points for the most dissatisfied.
次要结局
未报告次要终点
研究者
Bo Wang,MD
clinical Professor
Fujian Medical University