A randomized study to compare the effect of low-dose Ketamine versus Fentanyl on the hemodynamic response to laryngoscopy and endotracheal intubation.
Phase 4
- Conditions
- Health Condition 1: 3- AdministrationHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2024/07/071287
- Lead Sponsor
- SMS Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Elective Surgery under General Anaesthesia
Patient willing to give informed and written consent
Age group between 18-50
ASA grade 1&2
Exclusion Criteria
1. History of allergy or contraindications of any study drug
2. Patients scheduled for emergency surgery
3. Hypertension - known or previously dignosed
4. Pregnancy
5. Dementia or psychiatric illness
6. Known Ischemic heart disease
7. Raised intracranial pressure or intracranial pathology where a rise in intracranial pressure would pose a risk or patients scheduled for neurosurgical procedures
8. History or indicator of or proven difficult ventilation or laryngoscopy or intubation
Intubation time more than 30 seconds or repeated attempts at intubation 9
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HypertensionTimepoint: At baseline when patient comes to Operation theatre, post induction- within 1 minute of giving induction agent, during laryngoscopy, just after intubation and at 2, 4, 6, 8,10 minutes interval after intubation
- Secondary Outcome Measures
Name Time Method Tachycardia , post induction hypotension & any side effectsTimepoint: At baseline, post induction, during laryngoscopy, just after intubation & for 10 minutes at 2 minutes interval