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assessment of immune system during Low Calorie Diet induced weight loss

Not Applicable
Conditions
Obesity.
Simple obesity NOS
Registration Number
IRCT2014052617872N1
Lead Sponsor
Mashhad University of Medical Scienses
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Other
Sex
Female
Target Recruitment
29
Inclusion Criteria

Female; Age 25-40years; BMI = 30.00; Normal thyroid function; Normal blood cortisol; Normal mensturation; Healthy individuals(without any certain diseases); Normal HbA1c; Normal blood glucose test; Non smokers; non alcohol consumption
Exclusion criteria:Any drug consumption; Anemic Individuals

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
T Lymphocyte CD4+. Timepoint: Befor and after the intervention (Day 0 of intervention and after 10-15% weight loss). Method of measurement: flow cytometry.;T Lymphocyte CD3+. Timepoint: Befor and after the intervention (Day 0 of intervention and after 10-15% weight loss). Method of measurement: flow cytometry.;B Lymphocyte CD19+. Timepoint: Befor and after the intervention (Day 0 of intervention and after 10-15% weight loss). Method of measurement: flow cytometry.;Natural Killer Cells CD16/56+. Timepoint: Befor and after the intervention (Day 0 of intervention and after 10-15% weight loss). Method of measurement: flow cytometry.;T Lymphocyte CD8+. Timepoint: Befor and after the intervention (Day 0 of intervention and after 10-15% weight loss). Method of measurement: flow cytometry.
Secondary Outcome Measures
NameTimeMethod
Zinc. Timepoint: Befor and after the intervention (Day 0 of intervention and after 10-15% weight loss). Method of measurement: Blood test.;Iron. Timepoint: Befor and after the intervention (Day 0 of intervention and after 10-15% weight loss). Method of measurement: Blood test.
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