Evaluation of the immune system in older adults that receive a nutritional complement enriched with beta glucans extracted from the fungus Ganoderma lucidum
Completed
- Conditions
- Improvement in the baseline levels of immune system components in older adults.Not Applicable
- Registration Number
- ISRCTN53126301
- Lead Sponsor
- Progal-BT SAS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Adults aged 65-85 attached to the Elderly Welfare Center, San Bernardo - Berta Arias Foundation, Botero (FUNDARIAS) (Centro de Bienestar al Anciano San Bernardo, Fundación Berta Arias de Botero (FUNDARIAS)).
Exclusion Criteria
1. Refuse to sign and acept the informed consent
2. Not within the General and Social Health Care System of Colombia
3. Use of corticosteroids or any other medical or pharmaceutical intervention
4. Anticoagulant treatment, stent, valve replacement, history of stroke
5. Diabetes
6. Mental impairments
7. Malnutrition or malnutrition risk
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measured in blood sample at baseline then 12 weeks after intervention: <br>1. CD4+ and CD8+ T lymphocytes counts, measured by flow cytometry in whole blood collected<br>2. NK cells counts, measured by flow cytometry (CD16+/CD56+)
- Secondary Outcome Measures
Name Time Method 1. Haemoleucogram measured by flow cytometry<br>2. Serum IgA measured by immunoturbidimetry<br>3. Lipid profile measure by enzymatic colorimetric assay<br>4. Glucose levels measured by ultraviolet test<br>5. Nutritional and anthropometric measurements: body mass index (BMI)