Comparison of drugs norepinephrine & phenylephrine in elderly patients for avoidance of fall in blood pressure & heart rate after spinal anaesthesia
Phase 4
- Registration Number
- CTRI/2023/09/057603
- Lead Sponsor
- AIIMS , New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Informed written consent
2.ASA 1,2,3
3.Posted for elective surgery under spinal anesthesia
Exclusion Criteria
1.Patient refusal to participate
2.LVEF <40%
3.Uncontrolled hypertension
4.Allergy to the study drugs
5.CKD 3 or above
6.CLD with fluid retention
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in incidence of hemodynamic instability. Hemodynamic instability defined as either 1 or more of <br/ ><br>1. Fall in MAP by more than 20% <br/ ><br>2.Fall in SBP below 90mm of Hg <br/ ><br>3.Fall in HR below 50/minTimepoint: Entire duration of surgery starting immediately after spinal anaesthesia
- Secondary Outcome Measures
Name Time Method 1.Timing of hemodynamic instability <br/ ><br>2.Cardiac output & cardiac index in all patients <br/ ><br>3.Incidence of post operative nausea vomiting <br/ ><br>4.Incidence of post operative shivering <br/ ><br>5.Incidence of side effects of drugs Hypertension , TachycardiaTimepoint: During surgery starting immediately after spinal anaesthesia till 30 min post operatively