A Comparison of Colonic Bile Acid Content Following Right and Left Colectomies

• Conditions: Bile Acid and Salts; Colectomy

• Registration Number: NCT02596516
• Lead Sponsor: Meir Medical Center

Brief Summary

The aim of this study is to evaluate whether there is a difference in the bile acid content in the bowel in patients after right versus left colectomy. There is compelling evidence that patients under going resection of the right colon versus left coolon have a lower polyp detection rate in surveillance colonoscopies. The investigators intend to evaluate feces of patients undergoing left and right colectomies; prior to their surgery and again three and six months aftet the surgery. The investigators plan to compare the content of the different bile acids and to compare the content between the two groups.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Status Verified: 2015-11
• Study First Submitted: 2015-11-02
• Study First Submitted QC: 2015-11-02
• Study First Posted: 2015-11-04
• Last Update Submitted: 2015-11-05
• Last Update Posted: 2015-11-06
• Study Start: 2015-12
• Primary Completion: 2017-01
• Study Completion: 2020-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age above 18.
• Patients intended to undergo a colectomy for colonic cancer
• Patients willing and participate and able to sign an informed consent

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Exclusion Criteria

• Age under 18.
• Patients with Inflammatory Bowel Disease (Crohn's, Ulcerative colitis).
• Patients refusing to participate or are unable to understand or sign an informed consent

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Colonic bile acid content	two years