NCT06568783尚未招募2 期
Evaluation of Patients With Refractory Dermatomyositis Using [18F]- Fibroblast Activation Protein Inhibitor-74 (FAPI-74) PET/MRI Imaging
Farshad Moradi1 个研究点 分布在 1 个国家目标入组 21 人开始时间: 2024年12月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Rate of [18F]-FAPI-74 uptake.
研究概览
简要总结
This study proposes the use of a PET isotope, [18F]-Fibroblast Activation Protein Inhibitor-74, for a prospective single-center, single-arm study using MRI imaging for participants with Refractory Dermatomyostitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with suspected dermatomyositis.
- •Patient must be > 18 years old.
- •Be willing and able to provide written informed consent for the trial.
排除标准
- •Women who are pregnant or potentially pregnant per the Department of Radiology Policy on Imaging in Potentially Pregnant and Pregnant Women.
- •Contraindication to MRI or inability to lie flat for 30 min
- •Any serious medical condition that in the opinion of principal investigator could pose significant risk of harm or injury to the patient if they participate in the study
研究组 & 干预措施
[18F]-FAPI-74 PET/ MRI
Experimental
Participant receive [18F]-FAPI-74 injection and approximately 45-60 minutes later receive a MRI scan from vertex to legs, followed by a static PET emission scan over the same area.
干预措施: [18F]-FAPI-74 (Drug)
结局指标
主要结局
Rate of [18F]-FAPI-74 uptake.
时间窗: up to 1 hour
write the outcome title, how it will be measured.
次要结局
未报告次要终点
研究者
Farshad Moradi
Clinical Associate Professor
Stanford University
研究点 (1)
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