Influence of Specific Collagen Peptides on Recovery After Exercise Induced Muscle Damage

Not Applicable

Completed

• Conditions: Recovery
• Interventions: Dietary Supplement: Collagen; Other: Concurrent training

• Registration Number: NCT05220371
• Lead Sponsor: University of Vienna

Brief Summary

The present study aims at investigating the potential influence of specific collagen peptides on recovery after exercise induced muscle damage with focus on long-term effects.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-28
• Study First Submitted: 2022-01-28
• Study First Submitted QC: 2022-01-28
• Study First Posted: 2022-02-02
• Primary Completion: 2023-06-30
• Study Completion: 2023-06-30
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-23
• Last Update Posted: 2023-08-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 50

Inclusion Criteria

• No subjective symptoms during physical exertion
• Stable weight and dietary behaviour
• Body Mass Index (BMI) between 18.5 and 24.9
• No extensive strength/endurance sports so far (less than 3 h/week)
• No complaints during strenuous physical activity

Exclusion Criteria

• Circumstances that impair/prevent sporting activity (e.g. chronic heart disease, arrhythmia, heart valve disease, arthritis etc.)
• Intolerance/aversion to animal protein
• Arterial hypertension (high blood pressure) (syst > 200 mmHg and/or diast > 105 mmHg) at rest
• Presence of insulin-dependent diabetes mellitus
• Liver and/or kidney disease that precludes a high protein load
• Collagen supplementation or regular intake of other dietary supplements in the last 6 months.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Collagen	Concurrent training	15g of collagen peptides ingested daily
Placebo	Concurrent training	15g of Placebo ingested daily
Collagen	Collagen	15g of collagen peptides ingested daily

Primary Outcome Measures

Name	Time	Method
Change in Achilles tendon cross-sectional area	Baseline and after 12 weeks	Measured by ultrasound
Change in Vastus Lateralis fibre length	Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours)	Measured by ultrasound
Change in collagen related blood markers	Baseline (pre, post, 2 hours, 24 hours, 48 hours) and after 12 weeks (pre, post, 2 hours, 24 hours, 48 hours)	Measured by blood analysis
Change in body composition parameters (fat mass, fat-free mass, extracellular mass, body cell mass)	Baseline and after 12 weeks	Measured by bioelectrical impedance analysis
Change in maximal voluntary contraction (MVC)	Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours)	Measured by isokinetic dynamometer
Change in rate of force development (RFD)	Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours)	Measured by isokinetic dynamometer
Change in countermovement jump height (CMJ)	Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours)	Measured by force plate
Change in subjective pain score	Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours)	Measured by visual analogue scale
Change in Achilles tendon echo intensity	Baseline and after 12 weeks	Measured by ultrasound
Change in Vastus Lateralis echo intensity	Baseline and after 12 weeks	Measured by ultrasound

Trial Locations

Locations (1)

University of Vienna, Institute of Sport Science; 🇦🇹 Vienna, Austria