Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 59
- 试验地点
- 3
- 主要终点
- Length in days of hospital stay
研究概览
简要总结
Hypoxemic pneumonia is a major cause of hospitalization in Pulmonology. The patient's dependency on oxygen prevents early discharge from the hospital. An automated oxygen therapy is a system that allows administration of oxygen with a flow that is automatically adjusted to the patient's saturation, which is continuously monitored. This system has proven to be particularly effective with chronic obstructive pulmonary disease (COPD) patients, by decreasing the time spent in hypoxia and hyperoxia, and by accelerating the weaning of oxygen. Our hypothesis is that automated oxygen therapy leads to a diminution on the length of hospital stay.
详细描述
Prolonged hospitalization has many consequences, including loss of autonomy and nosocomial infection. Moreover, these complications themselves lead to an extension of the length of stay. This has an impact on the cost of care: several studies have shown that hospitalization is the most costly factor in the management of pneumonia, and that even a small amount of hospital stay, led to significant financial savings. Automated oxygen therapy is a device that automatically adjusts with the saturation the amount of oxygen administered. Investigator hypothesis is that automated oxygen therapy could shorten the length of stay of patients hospitalized for hypoxemic pneumonia. One group of patients will receive the automated oxygen therapy and the other group will receive the standard Oxygen therapy. The investigator will compare in each group the average length of stay, the duration of oxygen therapy, the time spent outside of the target saturation, the cost on the medical-economic level and the patient's experience.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient living at home or in an institution
- •Patient hospitalized for less than 48 hours
- •Pneumonia defined (according to the 2006 French-speaking infectious pneumology society (SPILF) criteria) by:
- •respiratory functional symptoms (cough, sputum, dyspnea, chest pain) and
- •Hyperthermia >38,5°C or hypothermia <36°C and
- •Radiological Signs of Pneumonia
- •Hypoxia : SpO2 < 94% in ambient air and/or PaO2< 60 mmHg in ambient air
排除标准
- •Pneumonia acquired at the hospital.
- •Patient hospitalized in another department more than 48 hours before admission
- •Chronic respiratory failure
- •Active neoplasia
- •Patients undergoing oxygen therapy and / or long-term NIV
- •Associated cardiac decompensation (clinical signs and / or NTproBNP> 1800ng / mL) (3
- •Initial Need for high flow oxygen therapy or ventilatory support (NIV, VI)
- •Difficulties expected from home support.
研究组 & 干预措施
Automated oxygen therapy
An automated oxygen therapy is a system that allows administration of oxygen with a flow that is automatically adjusted to the patient's saturation, which is continuously monitored. Patients will receive O2 automated intervention.
干预措施: O2 automated (Device)
Standard Oxygen therapy
Patients will receive O2 standard therapy
干预措施: O2 standard (Device)
结局指标
主要结局
Length in days of hospital stay
时间窗: 1 month
measure of total days of hospitalization and intensive care
次要结局
- quality questionnaire of patient's life during hospitalization(1 month)
- Time spent outside of the target saturation(1 month)
- rate of medical complication(1 month)
- Duration of oxygen therapy(1 month)
- the cost on the medical-economic level(1 month)