Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia
- Conditions
- PneumoniaLength of StayPneumonia, Ventilator-Associated
- Interventions
- Device: O2 standardDevice: O2 automated
- Registration Number
- NCT03527992
- Lead Sponsor
- University Hospital, Toulouse
- Brief Summary
Hypoxemic pneumonia is a major cause of hospitalization in Pulmonology. The patient's dependency on oxygen prevents early discharge from the hospital. An automated oxygen therapy is a system that allows administration of oxygen with a flow that is automatically adjusted to the patient's saturation, which is continuously monitored. This system has proven to be particularly effective with chronic obstructive pulmonary disease (COPD) patients, by decreasing the time spent in hypoxia and hyperoxia, and by accelerating the weaning of oxygen. Our hypothesis is that automated oxygen therapy leads to a diminution on the length of hospital stay.
- Detailed Description
Prolonged hospitalization has many consequences, including loss of autonomy and nosocomial infection. Moreover, these complications themselves lead to an extension of the length of stay. This has an impact on the cost of care: several studies have shown that hospitalization is the most costly factor in the management of pneumonia, and that even a small amount of hospital stay, led to significant financial savings. Automated oxygen therapy is a device that automatically adjusts with the saturation the amount of oxygen administered. Investigator hypothesis is that automated oxygen therapy could shorten the length of stay of patients hospitalized for hypoxemic pneumonia. One group of patients will receive the automated oxygen therapy and the other group will receive the standard Oxygen therapy. The investigator will compare in each group the average length of stay, the duration of oxygen therapy, the time spent outside of the target saturation, the cost on the medical-economic level and the patient's experience.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 128
-
Adult
-
Patient living at home or in an institution
-
Patient hospitalized for less than 48 hours
-
Pneumonia defined (according to the 2006 French-speaking infectious pneumology society (SPILF) criteria) by:
- respiratory functional symptoms (cough, sputum, dyspnea, chest pain) and
- Hyperthermia >38,5°C or hypothermia <36°C and
- Radiological Signs of Pneumonia
-
Hypoxia : SpO2 < 94% in ambient air and/or PaO2< 60 mmHg in ambient air
- Pneumonia acquired at the hospital.
- Patient hospitalized in another department more than 48 hours before admission
- Chronic respiratory failure
- Active neoplasia
- Patients undergoing oxygen therapy and / or long-term NIV
- Associated cardiac decompensation (clinical signs and / or NTproBNP> 1800ng / mL) (3
- Initial Need for high flow oxygen therapy or ventilatory support (NIV, VI)
- Difficulties expected from home support.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Standard Oxygen therapy O2 standard Patients will receive O2 standard therapy Automated oxygen therapy O2 automated An automated oxygen therapy is a system that allows administration of oxygen with a flow that is automatically adjusted to the patient's saturation, which is continuously monitored. Patients will receive O2 automated intervention.
- Primary Outcome Measures
Name Time Method Length in days of hospital stay 1 month measure of total days of hospitalization and intensive care
- Secondary Outcome Measures
Name Time Method quality questionnaire of patient's life during hospitalization 1 month Investigator want to evaluate the quality of life during hospitalization between patient in arm "Automated oxygen therapy" and patient in arm "Standard Oxygen therapy"
Time spent outside of the target saturation 1 month Investigator want evaluate the time spent outside of the target saturation by patient, during their hospitalization,
rate of medical complication 1 month Investigator want to evaluate the rate of medical complication between patient in arm "Automated oxygen therapy" and patient in arm "Standard Oxygen therapy"
Duration of oxygen therapy 1 month Oxygen therapy time evaluation during hospitalization of patient
the cost on the medical-economic level 1 month investigator want evaluate the cost of hospitalization between patient in arm "Automated oxygen therapy" and patient in arm "Standard Oxygen therapy"
Trial Locations
- Locations (1)
CHU Larrey
🇫🇷Toulouse, France