A Comparative Study to Evaluate Two Different Doses of Epidural Tramadol for Postoperative Analgesia in Patients Undergoing Upper Abdominal Surgery
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1.To compare duration of analgesia in both groups
研究概览
简要总结
The aim of postoperative analgesia is to provide subjective comfort with minimum side effects, with early ambulation and restoration of function. In upper abdominal surgery, the severity of postoperative pain is higher and it restricts the movement of diaphragm which increases the incidence of respiratory complications, hospital stay, surgical morbidity and mortality in these surgeries. Regional analgesia techniques like epidural analgesia with the introduction of local anaesthetics or opioids or mixture of the two in the epidural space is an established method of effective postoperative analgesia. Tramadol hydrochloride is an atypical centrally acting opioid with mixed opioid and non-opioid activity. Epidural tramadol has the benefit of lack of respiratory depresssant effect along with prolonged postoperative pain relief. The aim of the present study is to find out an optimum dose of tramadol hydrochloride to be used epidurally in upper abdominal surgery patients, based on body weight.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA grade I and II, Patients scheduled for upper abdominal surgeries, Elective surgeries.
排除标准
- •ASA grade III, IV and V Age less than 18 and more than 60 years Patients refusing to give consent Patients who are pregnant or lactating Patients having any bleeding diathesis or are on anticoagulant therapy.
结局指标
主要结局
1.To compare duration of analgesia in both groups
时间窗: 24 hours postoperative
2.To study postoperative pain relief in both groups (by numerical rating scale for pain intensity)
时间窗: 24 hours postoperative
次要结局
- 1.To compare postoperative complication in both groups.(2.Postoperative hemodynamic parameters in both groups.)
研究者
Diya Rajan
B J Medical College, Ahmedabad
