Effect of subcutaneous application of Helleborus niger in elderly patients with dementia - a retrospective cohort pilot study

• Conditions: dementia; F03; Unspecified dementia

• Registration Number: DRKS00033972
• Lead Sponsor: Geriatrische Rehabilitationsklinik Alexander von Humboldt

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-03-02
• Study Start: 2024-03-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 79

Inclusion Criteria

1. Diagnosis of dementia according to the Mini-Mental Status Examination (= 26 MMSE score)
2. Impairment of cognitive function measured with DemTect or Shulman clock test (= 12 DemTect score or Shulman clock test score =3)

Exclusion Criteria

Insufficient knowledge of the German language

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pre/post change in MMSE score (Mini Mental State Examination)

Secondary Outcome Measures

Name	Time	Method
Pre/post change in DemTect (dementia detection)<br>Pre/post change in Shulman clock-drawing test<br>Pre/post change in GDS (geriatric depression scale)