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Clinical Trials/NL-OMON52313
NL-OMON52313
Recruiting
Not Applicable

Endobiliary radiofrequency ablation for malignant biliary obstruction due to perihilar cholangiocarcinoma: a randomized controlled trial - RACCOO

Amsterdam UMC0 sites73 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Amsterdam UMC
Enrollment
73
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
Amsterdam UMC

Eligibility Criteria

Inclusion Criteria

  • \- 18 years or older.
  • \- Capable of providing written and oral informed consent.
  • \- Histological or cytological proof of perihilar cholangiocarcinoma
  • (adenocarcinoma).
  • \- Perihilar biliary obstruction with indication for drainage with uSEMS.\*
  • \- Advanced (no candidate for surgical resection) due to metastases, vascular or
  • lymph node (N2\). involvement on imaging or during staging laparoscopy according
  • to multidisciplinary team (MDT).
  • \*Only patients with pCCA are eligible however in case of reasonable doubt
  • between intrahepatic CCA with a perihilar biliary obstruction or massforming

Exclusion Criteria

  • \- Patients who potentially qualify for curative resection of pCCA.
  • \- pCCA eligible for liver transplantation.
  • \- Life\-expectancy less than 3 months.
  • \- ERCP and PTC technically not feasible.
  • \- Uncontrolled coagulopathy (PTT \>1,5x prolonged or thrombocytes below
  • 40\*10E9/L).
  • \- Ongoing cholangitis or liver abscess. Patients are required to be off
  • antibiotic treatment for cholangitis and/or liver abscess at least 7 days.
  • \- Any condition that is unstable or that could jeopardize the safety of the
  • subject and their compliance in the study.

Outcomes

Primary Outcomes

Not specified

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