JPRN-UMIN000024712已完成未知
Protective Effects of Bisoprolol against Acute Exacerbation in Moderate-to-Severe Chronic Obstructive Pulmonary Disease - Effects of Bisoprolol on Acute Exacerbation of COPD
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 35
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 40years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •(1) patients with severe (NYHA grade 3 or 4) cardiac failure (2) left ventricular contractility of 40% or less (3) 2nd/3rd-degree atrioventricular block, sinoatrial block or sick sinus syndrome (4) variant angina pectoris (5) severe peripheral circulatory disturbance (6) pulmonary hypertension from right cardiac failure (7) a history of pulmonary resection (8) malignancy of disease-free interval of less than 3 years (9) systolic blood pressure of less than 100 mmHg (10) cardiac rate of less than 60 bpm on a constant basis (11) uncontrolled diabetic mellitus (12) thyrotoxicosis (13) pheochromocytoma (14) psoriasis (15) use of supplemental oxygen or with SpO2 of less than 90%(or PaO2 of less than 60 Torr) (16) asthma (17) active interstitial pneumonia (18) COPD exacerbation or respiratory infection within 4 weeks before registration (19) pregnant women (20) current use of beta-blocker (21) history of hypersensitivity to bisoprolol (22) patients considered to be inappropriate for this study by attending physician
研究者
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