Effects of the addition of haloperidol on propofol requirements during sedation with propofol and remifentanil - ND

POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI0 个研究点开始时间: 2009年1月7日最近更新: 2014年2月10日

适应症

试验速览

暂无简介。

•) need for sedation and for mechanical ventilation through an endotracheal tube for more than 48 hours, b) ability to tolerate assisted ventilation. This latter criterion will be evaluated with a test with pressure support ventilation (ventilatory settings: pressure support 15 cmH2O and positive end-expiratory pressure 5 cmH2O) for 30 minutes. The test will be considered passed if the patient will maintain a respiratory rate < 30 breaths/min, a tidal volume > 6 mL/Kg and hemodynamic stability.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•a) age lower than 50 or higher than 80 years; b) women in fertile age; c) neurologic diseases (e.g., seizures), porphyria, hyperthyroidism; d) actual treatment with lithium, amiodarone, or tricyclic antidepressants; e) arrhythmias or corrected QT > 470 msec; f) Body Mass Index > 30.

发起方

POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI