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The Role of Netrin -1 in Acute Coronary Syndrome

Not Applicable
Completed
Conditions
Acute Coronary Syndrome
Registration Number
NCT04027127
Lead Sponsor
Aksaray University Training and Research Hospital
Brief Summary

In our study, Netrin -1; We found that patients with ACS increased at the time of admission, decreased TIMI 3 flow after angiography, and higher risk groups in high risk groups such as TIMI and GRACE were found to have higher Netrin-1 levels.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
238
Inclusion Criteria
  • Patients over the age of 18
  • diagnose ACS
  • patients undergoing angiography
Exclusion Criteria
  • CVE history
  • Neurological disease
  • Pregnancy and Lactation
  • Liver failure
  • Diagnosed malignity
  • Use of anticonvulsant and nephrotoxic medication
  • Chronic kidney disease
  • Not having angiography
  • Developing acute renal failure after angiography
  • Patients who rejected to participate were excluded.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
serum netrin-1 value30 minute

Netrin-1 in plasma was measured by enzyme-linked immunosorbent assay (ELISA) (Mybıosource MBS044526 ) All assays were performed in duplicate. Plasma Netrin-1 is expressed in picograms (pg) per mg.

Secondary Outcome Measures
NameTimeMethod

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