Skip to main content
Clinical Trials/NCT03673475
NCT03673475
Completed
Not Applicable

Internal Jugular Vein Distensibility and Pleth Variability Index for Evaluating Fluid Responsiveness

Tepecik Training and Research Hospital1 site in 1 country40 target enrollmentFebruary 1, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Intravascular Volume
Sponsor
Tepecik Training and Research Hospital
Enrollment
40
Locations
1
Primary Endpoint
number of patients with significant change in VJI distensibility and pleth variebility index
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Assessment of intravascular volume status is crucial in order to predict the efficacy of volume status in major abdominal surgery. The aim of the study is to verify the feasibility and usefulness of the internal jugular vein distensibility index as an adjunct to the pleth variebility index(PVI) to predict fluid responsiveness in major abdominal surgery.

Detailed Description

Forty patients above age 18 and ASA status I-III who are undergoing major abdominal surgery will be enrolled in the study. patients with right heart failure, arrythmia, severe valve stenosis or regurgitation will be excluded. After induction of general anesthesia, when the patients are hemodynamically stabilised, PVI and jugular vein distensibility will be calculated and recorded. after volume load with 500 ml gel infusion(in 15 min), measurements will be repeated within 10 minutes and recorded. Patients will be allocated to 2 groups according to the change in mean arterial pressure(MAP) after volume expansion: Responders will be defined as an increase in MAP by \>%10; while nonresponders will be defined as an increase in MAP \<%10 or decrease in MAP.

Registry
clinicaltrials.gov
Start Date
February 1, 2018
End Date
September 30, 2018
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Tepecik Training and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

MELTEM CAKMAK

Anesthesiologist

Tepecik Training and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • American Society of Anesthesiologists(ASA) physical status I-III patients
  • patients undergoing major abdominal surgery

Exclusion Criteria

  • arrythmia
  • severe right ventricle failure

Outcomes

Primary Outcomes

number of patients with significant change in VJI distensibility and pleth variebility index

Time Frame: during surgery at day 0

volume responders with significant change in jugular vein distensibility and pleth variebility index

Study Sites (1)

Loading locations...

Similar Trials