NCT04635644已完成不适用
Ultrasound Guided Erector Spinae Block Versus Intrathecal Morphine for Postoperative Analgesia in Major Hepatopancreaticobiliary Surgery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Cumulative opioid consumption
研究概览
简要总结
To compare the efficacy of USG-guided bilateral Erector spinae plane block (ESPB) with intrathecal morphine (ITM) for postoperative analgesia after major hepatopancreaticobiliary surgery (HPB)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 65 years with a body mass index (BMI) of 18-35 kg/m2,
- •patients with the American Society of Anesthesiologists (ASA) physical status I - II,
- •Patients scheduled for elective major hepatopancreaticobiliary surgery for benign or malignant disease; major surgery is defined as an operation of anticipated duration of more than one hour.
排除标准
- •Patient's refusal
- •Allergy or contraindications to the study drugs,
- •Infection at the site of injection,
- •Coagulopathy,
- •Psychiatric disorders
- •Severely co-morbid patients,
- •Chronic pain syndromes,
- •Prolonged opioid medication,
结局指标
主要结局
Cumulative opioid consumption
时间窗: 24 hours postoperatively
Nalbuphine consumption in mg equivalent to morphine dose
次要结局
- Analgesic drug consumption other than nalbuphine(at 8, 24, 48, and 72 hours postoperatively.)
- Numerical Rating Scale (NRS) at rest and when coughing(at 1, 2, 4, 8, 12, 24, 48 and 72 hours postoperatively)
- Heart Rate(Intraoperatively)
- Incidence of Postoperative nausea & vomiting (PONV)(24 hours postoperatively)
- Nalbuphine consumption in mg(at 8, 48, and 72 hours postoperatively.)
- Mean Arterial Pressure(Intraoperatively)
研究者
Magdy Mohammed Mahdy Sayed
Principal Investigator
Assiut University
研究点 (2)
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