Endorectal Coil Magnetic Resonance Images (ERC-MRI)
Phase 2
Completed
- Conditions
- Prostatic Neoplasms
- Registration Number
- NCT00160953
- Lead Sponsor
- University Health Network, Toronto
- Brief Summary
When we acquired MR images of the prostate gland using a coil (receiver antenna) inside the rectum, we can see areas with tumour in the prostate gland, and well as details of the anatomy. The coil inside the rectum changes the shape of the prostate gland. In order to use this images to help target radiation therapy to the tumour better, we need to deform the images to the original shape of the prostate gland without the coil. In this study, we will develop a way to deform the images accurately.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria
- adenocarcinoma of the prostate
- patient undergoing dose escalated conformal EBRT
- low or intermediate risk prognostic factors: PSA < or equa to20, gleason score <8, T <T3, N category 0 or X, M category 0 or X
- > or equal to 18 years of age
- ECOG performance status 0 or 1
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Exclusion Criteria
- contraindications to MRI
- bleeding diathesis and anti-coagulative therapy that cannot be temporarily ceased precluding insertion of fiducial markers
- IFB or collagen vascular disease
- previous colorectal surgery
- previous pelvic RT
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method The primary aim of this study is to develop a prostate deformation model using the finite element method from anatomic MR images of the prostate gland acquired with and without ERC.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Princess Margaret Hospital
🇨🇦Toronto, Ontario, Canada