Mothers Living With HIV and Their Adolescent Children

Not Applicable

Completed

• Conditions: Physical Health; Family Relations; Risky Sexual Behavior; Mental Health; Substance Use; HIV Infections

• Registration Number: NCT00988390
• Lead Sponsor: University of California, Los Angeles

Brief Summary

* Context: Mothers living with HIV (MLH) and their children face predictable challenges: maintaining physical and mental health, parenting while ill, and addressing HIV-related stressors.

* Objective: To evaluate the efficacy of a family-based intervention over time; to contrast the life adjustments of HIV-affected families and their non-HIV-affected neighbors in the current treatment era.

* Design: Randomized controlled trial of MLH and a longitudinal comparison of MLH to a neighborhood cohort using random effect regression.

* Participants and Intervention: MLH (n = 339) and their school-age children (n = 259) were randomly assigned to receive 1) an intervention of 16 sessions in a cognitive-behavioral, small-group format; or 2) control. MLH and their children were compared to non-HIV-affected families recruited at shopping markets. Participant retention was high: 84% at 6 months, 83% at 12 months, and 78% at 18 months.

* Main Outcome Measures: Family functioning and conflict, mental and physical health, sexual behavior, and substance use.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-02
• Primary Completion: 2008-06
• Study Completion: 2008-06
• Study First Submitted: 2009-10-01
• Study First Submitted QC: 2009-10-01
• Study First Posted: 2009-10-02
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-23
• Last Update Posted: 2016-11-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 543

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL