De-escalating Axillary Surgery in Breast Cancer Patients in Nigeria
Not Applicable
Not yet recruiting
- Conditions
- Breast CancerAxillaBreast
- Registration Number
- NCT06039956
- Lead Sponsor
- Nova Scotia Health Authority
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
Inclusion Criteria:<br><br> - Eligible to receive systemic chemotherapy<br><br>Must include all the following:<br><br> - Tany, cN1 at presentation<br><br> - Biopsy proven pN1 disease after axillary US<br><br> - cN0 after neoadjuvant chemotherapy<br><br>Exclusion Criteria:<br><br> - Previous / recurrent breast cancer<br><br> - Previous axillary and/or breast surgery<br><br> - Inflammatory breast cancer<br><br> - N2 disease or Stage IV disease
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method False-negative rate
- Secondary Outcome Measures
Name Time Method pathologic complete response rate;radiographic and clinical concordance;Sensitivity of pre-operative axillary US;Specificity of pre-operative axillary US;False negative rate of pre-operative axillary US;Sensitivity of single-agent sentinel lymph node biopsy;Specificity of single-agent sentinel lymph node biopsy;False negative rate of single-agent sentinel lymph node biopsy