Post operative sore throat after anaesthesia

Not yet recruiting

Conditions: elective surgery under general anaesthesia requiring endotracheal intubation

Registration Number: CTRI/2015/02/005535

Lead Sponsor: Department of Anaesthesiology Pain Perioperative Medicine

Brief Summary: Postoperative sore throat (POST) is a longstanding common negative anesthesia outcome after general anesthesia (GA) wherein conventional direct laryngoscopy-intubation (DLI) technique is employed to control upper airway. Various reasons have been placed forth and corresponding measures undertaken (e.g. tracheal tube cuff pressure control) to preclude/diminish the impact of POST but in vain. Till date, none of the efforts to prevent POST have considered mechanical factors associated with DLI as a contributing factor of POST. Since the only â€˜activeâ€™ mechanical event during upper airway management comprises DLI, we presume that modification of DLI technique will reduce the forces associated with the technique and consequently, bring down incidence/severity of POST. Tracheal tube introducers (TTI), introduced to facilitate intubation in difficult airway settings, have only been employed once to improve quality-of-DLI in non-difficult airway (NDA) settings, that too with limited success. We speculate that the forces related to DLI, including, 1. Laryngoscopic mandibular lift (to expose the glottis-opening), and 2. Frictional forces generated when a tracheal tube passes the vocal cords to get into the trachea; are likely to be lesser when a tracheal-tube is guided inside the trachea with the help of a TTI. This study intends to evaluate the use of TTI in NDA in terms of their ability to bring down the impact of active DLI forces during upper airway access, and consequently, on the incidence of POST.xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 450

Inclusion Criteria

ASA physical status I/II 2.Short-to-moderate duration surgery(up to 3-hours)under general anaesthesia with controlled ventilation.

Exclusion Criteria

1.Anticipated difficult airway.
2.Systemic illness with presenting complaints of sore/dry throat (diabetics with polydipsia, hypertensives on diuretics, moribund bed ridden patients).
3.Neurosurgical patients with active ICP considerations.
4.History of airway related morbidity (POST, mucosal trauma) 5.Recent head and neck, intraoral/nasal surgery.
6.Psychiatric and substance abuse patients.
7.Ongoing upper and lower respiratory tract inflammation/infection.
8.Bleeding diathesis, steroid dependence 9.Consent refusal.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To evaluate the impact of tracheal-tube introducer guided intubation on incidence of postoperative sore throat	From arrival in the postoperative recovery room till 24 hours

Secondary Outcome Measures

Name	Time	Method
1.Intubation attempts	2.Laryngoscopy-intubation time

Trial Locations

Locations (1): Department of Anaesthesiology Pain & Perioperative Medicine 5th Floor SSRB
🇮🇳
Central, DELHI, India
Department of Anaesthesiology Pain & Perioperative Medicine 5th Floor SSRB
🇮🇳Central, DELHI, India
Dr Amitabh Dutta
Principal investigator
09810848064
duttaamitabh@yahoo.co.in