NCT02952157Unknown4 期
Effect on Postoperative Sore Throat of Lidocaine Jelly Application Over the Endotracheal Tube of Tapered-shaped Cuff
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 入组人数
- 210
- 主要终点
- Number of participants with sore throat
研究概览
简要总结
Postoperative sore throat is a complication after general anesthesia requiring endotracheal intubation. The investigators will evaluate the efficacy of lidocaine jelly application on the endotracheal tube with taper-shaped cuff regarding postoperative sore throat.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I-III
- •Patients scheduled for general anesthesia with endotracheal intubation
- •Patients scheduled for surgery which duration is expected to less than 3 hr
排除标准
- •Difficult airway
- •Rapid sequence induction
- •Recent sore throat
- •Recent upper respiratory infection
- •Chronic obstructive pulmonary disease
- •Chronic cough
- •Pregnancy
- •Allergy to lidocaine
- •Friable teeth
- •History of head and neck surgery
- •Multiple intubation attempts
- •Regional anesthetic agents
- •Gastric tube
- •Dexamethasone
研究组 & 干预措施
Control
Sham Comparator
Normal saline will be applied to the endotracheal tube.
干预措施: Normal saline application (Drug)
Lidocaine
Active Comparator
Lidocaine jelly will be applied to the endotracheal tube.
干预措施: Lidocaine jelly application (Drug)
结局指标
主要结局
Number of participants with sore throat
时间窗: At 24 hr
次要结局
- Number of participants with hoarseness(At 1, 6, 12 and 24 hr)
- Number of participants with vomiting(At 1, 6, 12 and 24 hr)
- Number of participants with sore throat(At 1, 6, and 12 hr)
- Number of participants with additional pain medication(At 24 hr)
- Number of participants with throat numbness(At 1, 6, 12 and 24 hr)
- Number of participants with dry mouth(At 1, 6, 12 and 24 hr)
- Number of participants with cough(At 1, 6, 12 and 24 hr)
- Number of participants with nausea(At 1, 6, 12 and 24 hr)
研究者
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