Effect on Postoperative Sore Throat of Lidocaine Jelly Application Over the Endotracheal Tube of Tapered-shaped Cuff

Phase 4

• Conditions: Sore Throat
• Interventions: Drug: Normal saline application; Drug: Lidocaine jelly application

• Registration Number: NCT02952157
• Lead Sponsor: Keimyung University Dongsan Medical Center

Brief Summary

Postoperative sore throat is a complication after general anesthesia requiring endotracheal intubation. The investigators will evaluate the efficacy of lidocaine jelly application on the endotracheal tube with taper-shaped cuff regarding postoperative sore throat.

Detailed Description

Not available

Study Timeline

• Status Verified: 2016-10
• Study First Submitted: 2016-10-20
• Study First Submitted QC: 2016-10-30
• Last Update Submitted: 2016-10-30
• Study Start: 2016-11
• Primary Completion: 2016-11
• Study Completion: 2016-11
• Study First Posted: 2016-11-02
• Last Update Posted: 2016-11-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 210

Inclusion Criteria

• ASA I-III
• Patients scheduled for general anesthesia with endotracheal intubation
• Patients scheduled for surgery which duration is expected to less than 3 hr

Exclusion Criteria

• Difficult airway
• Rapid sequence induction
• Recent sore throat
• Recent upper respiratory infection
• Asthma
• Chronic obstructive pulmonary disease
• Chronic cough
• Pregnancy
• Allergy to lidocaine
• Friable teeth
• History of head and neck surgery
• Multiple intubation attempts
• Regional anesthetic agents
• Gastric tube
• Dexamethasone

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Normal saline application	Normal saline will be applied to the endotracheal tube.
Lidocaine	Lidocaine jelly application	Lidocaine jelly will be applied to the endotracheal tube.

Primary Outcome Measures

Name	Time	Method
Number of participants with sore throat	At 24 hr

Secondary Outcome Measures

Name	Time	Method
Number of participants with hoarseness	At 1, 6, 12 and 24 hr
Number of participants with vomiting	At 1, 6, 12 and 24 hr
Number of participants with sore throat	At 1, 6, and 12 hr
Number of participants with additional pain medication	At 24 hr
Number of participants with throat numbness	At 1, 6, 12 and 24 hr
Number of participants with cough	At 1, 6, 12 and 24 hr
Number of participants with dry mouth	At 1, 6, 12 and 24 hr
Number of participants with nausea	At 1, 6, 12 and 24 hr