Role of CRP/Albumin ratio in predicting post operative morbidity in Major GI surgeries
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- To assess the role of CRP/Albumin ratio in predicting post-operative morbidity.
研究概览
简要总结
To identify patients at risk and to optimizeperioperative care, a basic and reliable parameter representing surgical stressis crucial. In clinical settings, postoperative blood C-reactiveprotein (CRP) levels have been used to assess postoperative inflammatorystatus. However, the slow kinetics of CRP as a predictor of stress is amajor drawback. Peak values are noted only on days 2 or 3 following surgery,which may be too late for early preventive measures. Additionally, albumin is a common nutritional markerand outcome predictor exhibits a rapid response to surgical stress, making itan ideal tool for gauging and predicting a difficult postoperative course. Therefore, the CRP to albumin ratio will accuratelyreflect the nutritional and inflammatory condition and may act as a marker forthe stress response post-surgery and a possible indicator of unfavorableoutcomes.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patient undergoing Major elective gastrointestinal surgery in General Surgery Department, GIS Department and Onco-surgery Department at KH, Manipal 2.Patient consenting to be a part of the study.
- •3.Patient >18 years of age.
- •4.Patient undergoing neoadjuvant chemotherapy with no evidence of malnutrition preoperatively.
排除标准
- •1.Patient not willing to participate in the surgery.
- •2.Patient undergoing emergency GI surgery.
- •3.Patients undergoing surgeries which are not defined under “major†criteria ( eg.
- •lap chole ) according to WRHA criteria 4.Patient failing to follow up.
- •5.Patient <18 years of age.
- •6.Patient with existing chronic inflammatory conditions.
- •7.Patient’s with comorbidities causing organ dysfunction (eg-COPD,CKD) ( ASA grade 3 and above ) 8.Patient undergoing albumin infusion pre operatively 9.Patient discharging <48 hours of surgery 10.Patient with operative mortality.
结局指标
主要结局
To assess the role of CRP/Albumin ratio in predicting post-operative morbidity.
时间窗: 30 days of postoperative period
次要结局
- Relationship between CRP/Albumin ratio and(30 days morbidity.)