跳至主要内容
临床试验/CTRI/2022/04/041814
CTRI/2022/04/041814尚未招募2/3 期

A Randomized Comparative Clinical Study To Evaluate The Efficacy of Dadruhar Lepa and Raktamokshana (Jalaukavcharana) Along With Nimba-Patolapatra Kwath In The Management Of Dadru wsr To Tinea

Ayurvedic and Unani Tibbia College and Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2022年4月24日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Rookshata (Dryness)

研究概览

简要总结

Skin is considered as largest sense organ of the body and has many different functions. The skin functions in thermoregulation, protection, metabolic functions and sensation. Its size and external

location makes it susceptible to wide variety of disorders. In recent years, there has been a considerable increase in incidence of skin disease in tropical and developing countries like India. All the skin diseases in Ayurveda have been classified into Mahakustha and Kshudra Kustha. Dadru is one among the Kustha. Acharya Charak has included Dadru in Khsudra Kustha, whereas Acharya Sushruta and Acharya Vagbhata have explained under Mahakustha. It involves the clinical features like Kandu, Deergapratana, Utsanna, Mandala, Raaga, Pidika which exhibits  involvement of Kapha and Pitta. Acharaya Vagbhata especially mentioned Dadru as Anusangika. Acharaya Dalhana classified Dadru into Sitha and Asitha. Acharaya not explained separate Nidana for Dadru kustha. Ayurvedic Classics have considered each type of Kustha to be a Tridoshaja manifestation where Rasa, Rakta, Mamsa and Ambu are the main Dusya. Dadru, one of the most common but miserable variety of Kustha affects the population of all age group. On the basis of clinical appearance Dadru Kustha mostly simulates with ‘dermatophytosis.’ The dermatophytes are a group of closely related fungi that have the capacity to invade keratinized tissue (skin, hair, and nails) of humans and other animals to produce an infection, dermatophytosis, commonly referred to as ringworm. The infections caused by a dermatophyte (species of fungi belonging to the genera Trichophyton, Microsporum, or Epidermophyton) are referred to as Tinea.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Open Label

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patient willing to participate in the trial and sign the consent form.
  • 2.The patients between the age group of 18 to 60 years in either sex.
  • 5.Patient having Potassium hydroxide (KOH) scrapping test positive.

排除标准

  • 1.Patients who were not willing for trial or fail to give consent.
  • 2.Patients suffering from any other systemic illness,liver disorder, tuberculosis,bleeding disorder etc.
  • 3.Pregnant and lactating women.
  • 4.Patients taking antibiotic therapy for any systemic illness within 2 months.
  • 5.H/O of hypersensitivity of any trial drug.
  • 6.Allergic reaction to active substances of the leech such as hirudin,calin,hyaluronidase,egline,kollagenage,apyrase,destabilase,piyavit etc.
  • 7.Patients with genetic and endocrinal disorder, chronic disorder like paralysis, cancer, renal failure, hepatic failure and IHD.
  • 8.Patients having Tinea manuum and Tinea unguim.
  • 9.Raktamokshana (jalaukavcharana)will not be done in Patients having diabetes mellitus.

结局指标

主要结局

Rookshata (Dryness)

时间窗: 12 weeks

Udgata mandal (Elevated lesion)

时间窗: 12 weeks

Improvement in subjective parameters.

时间窗: 12 weeks

Raga (Inflammation)

时间窗: 12 weeks

Pidika (Eruption)

时间窗: 12 weeks

Daha (Burning sensation)

时间窗: 12 weeks

次要结局

  • Assessment will be done clinically on basis of decrease in subjective parameters of dadru(12 weeks)

研究者

发起方
Ayurvedic and Unani Tibbia College and Hospital
申办方类型
Government medical college

研究点 (1)

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